It should be "safe", but the real question is whether it'll taste good. That depends on a lot of factors - how good or bad the wine is, what kind, how old it is, etc...and whether you care. Taste it. If it tastes good to you, it's fine. I'll generally throw a bottle out after a week of being opened. If it still tastes "decent" but not great, you can cook with it and make a great sauce :-)
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